GASP‐2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP‐1 transgenics
نویسندگان
چکیده
منابع مشابه
Roles of GASP-1 and GDF-11 in Dental and Craniofacial Development.
PURPOSE Growth and differentiation factor-11 (GDF-11) is a TGF-β family member that plays important regulatory roles in development of multiple tissues which include axial skeletal patterning, palatal closure, and tooth formation. Proteins that have been identified as GDF-11 inhibitors include GDF-associated serum protein-1 (GASP-1) and GASP-2. Recently, we found that mice genetically engineere...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2020
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.201901220r